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<br>Get emergency medical assist when you have signs of a heart assault or stroke: chest ache spreading to your jaw or shoulder, sudden numbness or weakness on one facet of the physique, slurred speech, leg swelling, feeling short of breath. This isn't a complete record of negative effects and others might occur. Name your doctor for medical advice about side effects. What is an important info I should find out about naproxen? Naproxen can increase your threat of fatal heart assault or stroke, even when you haven't any danger factors. Don't use this medication simply before or after heart bypass surgical procedure (coronary artery bypass graft, or CABG). Naproxen may cause stomach or intestinal bleeding, which could be fatal. These conditions can happen with out warning while you're using naproxen, especially in older adults.<br><br>Potentially Fatal: Anaphylactic/anaphylactoid reactions. Exfoliative dermatitis, Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN). Hypersensitivity. Aspirin or NSAID allergy. Perioperative pain in the setting of CABG surgery. BLACK Box WARNING: Bear in mind that patient may be at increased danger for CV event, GI bleeding; monitor accordingly. Give with meals or after meals if GI upset happens.<br><br>Security and efficacy not established. 200 mg q 12 hr PO. Naproxen has anti-inflammatory, analgesic, antipyretic actions. It reduces prostaglandin synthesis by inhibiting the enzyme cyclooxygenase. It also inhibits platelet aggregation. Edema,  franks ([https://www.lurkerlounge.com/forums/user-120190.html https://www.lurkerlounge.com/]) palpitation, dizziness, drowsiness, headache, mild headedness, vertigo, pruritus, skin eruption, ecchymosis, purpura, rash, fluid retention, abdominal pain, constipation, nausea, heartburn, diarrhea, dyspepsia, stomatitis, flatulence, gross bleeding/perforation, indigestion, ulcers, vomiting, abnormal renal function, hemolysis, ecchymosis, anemia, increased bleeding time, elevated LFTs, visible disturbances, tinnitus, listening to disturbances, dyspnoea, diaphoresis, thirst.<br><br>Arrange for periodic ophthalmologic examination during lengthy-time period therapy. WARNING: If overdose occurs, institute emergency procedures-gastric lavage, induction of emesis, supportive therapy. Take drug with food or meals if GI upset occurs; take only the prescribed dosage. Dizziness, drowsiness can happen (keep away from driving or using dangerous equipment). Report sore throat; fever; rash; itching; weight acquire; swelling in ankles or fingers; adjustments in imaginative and prescient; black, tarry stools.<br><br>Assess blood pressure (BP) periodically and compare to regular values (See Appendix F). NSAIDs can enhance BP in sure patients. Be alert for indicators of extended bleeding time such as bleeding gums, nosebleeds, and unusual or extreme bruising. Report these signs to the physician. Assess peripheral edema utilizing girth measurements, volume displacement, and measurement of pitting edema (See Appendix N).<br>