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Get emergency medical assist when you have signs of a heart assault or stroke: chest ache spreading to your jaw or shoulder, sudden numbness or weakness on one facet of the physique, slurred speech, leg swelling, feeling in need of breath. This isn't an entire record of negative effects and others could occur. Name your physician for medical recommendation about unwanted side effects. What is the most important information I should learn about naproxen? Naproxen can increase your risk of fatal coronary heart attack or stroke, even when you haven't any risk components. Don't use this medication simply earlier than or after heart bypass surgical procedure (coronary artery bypass graft, or CABG). Naproxen may also trigger stomach or intestinal bleeding, which may be fatal. These circumstances can happen without warning if you are utilizing naproxen, particularly in older adults.

Potentially Fatal: Anaphylactic/anaphylactoid reactions. Exfoliative dermatitis, Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN). Hypersensitivity. Aspirin or NSAID allergy. Perioperative pain within the setting of CABG surgery. BLACK Box WARNING: Be aware that affected person could also be at elevated risk for CV event, GI bleeding; monitor accordingly. Give with meals or after meals if GI upset happens.

Safety and efficacy not established. 200 mg q 12 hr PO. Naproxen has anti-inflammatory, analgesic, antipyretic actions. It reduces prostaglandin synthesis by inhibiting the enzyme cyclooxygenase. It additionally inhibits platelet aggregation. Edema, palpitation, dizziness, drowsiness, headache, mild headedness, vertigo, pruritus, skin eruption, ecchymosis, purpura, rash, fluid retention, abdominal ache, constipation, nausea, heartburn, diarrhea, dyspepsia, stomatitis, flatulence, gross bleeding/perforation, indigestion, ulcers, vomiting, abnormal renal perform, hemolysis, ecchymosis, anemia, unsizableness (http://wyposazenie-kuchni.forum-opinie24.pl/) increased bleeding time, elevated LFTs, visual disturbances, tinnitus, hearing disturbances, dyspnoea, diaphoresis, thirst.

Arrange for periodic ophthalmologic examination throughout lengthy-term therapy. WARNING: If overdose occurs, institute emergency procedures-gastric lavage, induction of emesis, supportive therapy. Take drug with meals or meals if GI upset happens; take solely the prescribed dosage. Dizziness, drowsiness can occur (keep away from driving or the usage of harmful machinery). Report sore throat; fever; rash; itching; weight acquire; swelling in ankles or fingers; changes in imaginative and prescient; black, tarry stools.

Assess blood strain (BP) periodically and compare to normal values (See Appendix F). NSAIDs can improve BP in sure patients. Be alert for indicators of prolonged bleeding time similar to bleeding gums, nosebleeds, and unusual or extreme bruising. Report these indicators to the physician. Assess peripheral edema utilizing girth measurements, volume displacement, and measurement of pitting edema (See Appendix N).